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Thermal stability of cannabinoids in dried cannabis: a kinetic study.

Anal Bioanal Chem. 2021 Jan 08;:

Authors: Meija J, McRae G, Miles CO, Melanson JE

Abstract
This study was undertaken to quantitatively explore the effect of temperature on the degradation of cannabinoids in dried cannabis flower. A total of 14 cannabinoids were monitored using liquid chromatography and tandem mass spectrometry in temperature environments from - 20 to + 40 °C lasting up to 1 year. We find that a network of first-order degradation reactions is well-suited to model the observed changes for all cannabinoids. While most studies focus on high-temperature effects on the cannabinoids, this study provides high-precision quantitative assessment of room temperature kinetics with applications to shelf-life predictions and age estimates of cannabis products.

PMID: 33420535 [PubMed – as supplied by publisher]


Source: ncbi 2

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Categories: Medical

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