Trends Cancer. 2022 Mar 5:S2405-8033(22)00024-3. doi: 10.1016/j.trecan.2022.01.017. Online ahead of print.

ABSTRACT

Substantial preclinical evidence demonstrates the antiproliferative, cytotoxic, and antimetastatic properties of plant-derived cannabinoids (phytocannabinoids) such as cannabidiol and tetrahydrocannabinol. The cumulative body of research into the intracellular mechanisms and phenotypic effects of these compounds supports a logical, judicious progression to large-scale phase II/III clinical trials in certain cancer types to truly assess the efficacy of phytocannabinoids as anticancer agents.

PMID:35260379 | DOI:10.1016/j.trecan.2022.01.017


Source: ncbi

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