Can Vet J. 2022 Apr;63(4):423-426.


OBJECTIVE: We aimed to examine the effects of cannabidiol (CBD)-containing hemp oil without delta-9-tetrahydrocannabinol (THC) as a supplemental treatment for canine atopic dermatitis (CAD), as well as its adverse effects, and effects on concurrent drug use in dogs.

ANIMAL: In this retrospective case series, 8 dogs with CAD were diagnosed by veterinary dermatologists certified by the Japanese Society of Veterinary Dermatology.

PROCEDURE: The medical records of dogs supplemented with CBD-containing hemp oil were evaluated with respect to signalment, physical examination, plasma C-reactive protein concentrations, pharmacologic management, the CAD Extent and Severity Index (4th iteration), and the Pruritus Visual Analog Scale.

RESULTS: Overall, CBD, used as a supplement in combination with other drugs, was well-tolerated over a wide dose range and decreased the occurrence of pruritus in dogs with CAD when ingested twice a day.

CONCLUSION: This study provides the first report of supplementation with CBD without THC that was effective in controlling pruritic behavior in dogs with CAD.

CLINICAL RELEVANCE: Further controlled studies are required to investigate the dose range, efficacy, and safety.

PMID:35368394 | PMC:PMC8922375

Source: ncbi

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