Pediatr Clin North Am. 2021 Oct;68(5):977-990. doi: 10.1016/j.pcl.2021.05.005. Epub 2021 May 18. ABSTRACT Studies have yielded mixed findings regarding changes in adolescent substance use during the COVID-19 pandemic; some report increased alcohol and cannabis use, others show less binge drinking and vaping behaviors, and others no change. In 2019, only Read more…
Sociol Inq. 2021 Aug;91(3):668-695. doi: 10.1111/soin.12359. Epub 2020 Feb 13. ABSTRACT While states are implementing policies to legalize cannabis for medical or recreational purposes, it remains a Schedule 1 controlled substance with no medical uses according to US federal law. The perception of cannabis depends on social and cultural norms Read more…
Pain. 2021 Aug 26. doi: 10.1097/j.pain.0000000000002463. Online ahead of print. ABSTRACT Studies have shown that women are more susceptible to adverse effects (AEs) from conventional drugs. This study aimed to investigate the differences of medical cannabis (MC)-related AEs between women and men in patients with chronic noncancer pain (CNCP). This Read more…
Front Pharmacol. 2021 Sep 2;12:736511. doi: 10.3389/fphar.2021.736511. eCollection 2021. ABSTRACT The possible evolutionary trend of COVID-19 in South Africa was investigated by comparing the genome of SARS-CoV-2 isolated from a patient in KwaZulu-Natal, South Africa with those isolated from China, Spain, Italy, and United States, as well as the genomes Read more…
Front Pharmacol. 2021 Sep 2;12:736511. doi: 10.3389/fphar.2021.736511. eCollection 2021. ABSTRACT The possible evolutionary trend of COVID-19 in South Africa was investigated by comparing the genome of SARS-CoV-2 isolated from a patient in KwaZulu-Natal, South Africa with those isolated from China, Spain, Italy, and United States, as well as the genomes Read more…
J Clin Epidemiol. 2021 Sep 16:S0895-4356(21)00307-3. doi: 10.1016/j.jclinepi.2021.09.021. Online ahead of print. ABSTRACT OBJECTIVE: to assess the inter-rater reliability (IRR) of the revised Cochrane risk-of-bias tool for randomised trials (RoB2). METHODS: Four raters independently applied RoB2 on critical and important outcomes of individually randomized parallel-group trials (RCTs) included in the Read more…
J Pharm Biomed Anal. 2021 Aug 28;206:114346. doi: 10.1016/j.jpba.2021.114346. Online ahead of print. ABSTRACT Cannabis sativa L. is a plant known all over the world, due to its history, bioactivity and also social impact. It is chemically complex with an astonishing ability in the biosynthesis of many secondary metabolites belonging Read more…
Osteoarthritis Cartilage. 2021 Sep 16:S1063-4584(21)00888-8. doi: 10.1016/j.joca.2021.09.003. Online ahead of print. ABSTRACT OBJECTIVE: Joint injury-induced perturbations to the endocannabinoid system (ECS), a regulator of both inflammation and nociception, remain largely uncharacterized. We employed a mouse model of ACL rupture to assess alterations to nociception, inflammation, and the ECS while using Read more…
Sci Total Environ. 2021 Sep 14;805:150269. doi: 10.1016/j.scitotenv.2021.150269. Online ahead of print. ABSTRACT Evaluating consumption estimates for lipophilic drugs in wastewater has proven to be a challenge. A common feature for these compounds is that they are excreted in faeces and in conjugated form in urine. Limited research with no Read more…
Addict Behav. 2021 Aug 24;124:107097. doi: 10.1016/j.addbeh.2021.107097. Online ahead of print. ABSTRACT INTRODUCTION: Vaporised nicotine products (VNPs) may be useful smoking cessation aids for people in alcohol and other drug (AOD) treatment, a population with high tobacco-related morbidity and mortality rates. This qualitative study aimed to examine the barriers and Read more…