Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization.

augusta.edu.Abstract Inflammation is an important mediator of secondary neurological injury after traumatic brain injury (TBI). Endocannabinoids, endogenously produced arachidonate based lipids, have recently emerged as powerful anti-inflammatory compounds, yet the molecular and cellular mechanisms underlying these effects are poorly defined. Endocannabinoids are physiological ligands for two known cannabinoid receptors, CB1R Read more…

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Attitudes toward and knowledge of medical cannabis among individuals with spinal cord injury.

 353) of people with SCI. To determine if knowledge and attitudes are influenced by socio-demographic and injury-specific factors. Setting: Three academic medical centers in the US. Methods: Distribution of an online survey through email lists maintained by 3 SCI centers. Results: Participants largely believed that cannabis use is safe, has Read more…

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