A systematic survey showed important limitations in the methods for assessing drug safety among systematic reviews. J Clin Epidemiol. 2020 Apr 01;: Authors: Li L, Deng K, Busse JW, Zhou X, Xu C, Liu Z, Ren Y, Zou K, Sun X Abstract OBJECTIVES: To examine the design, conduct, and analysis Read more…
A Systematic Review of the Effects of Perinatal Alcohol Exposure and Perinatal Marijuana Exposure on Adult Neurogenesis in the Dentate Gyrus. Alcohol Clin Exp Res. 2020 Apr 04;: Authors: Reid HMO, Lysenko-Martin MR, Snowden TM, Thomas JD, Christie BR Abstract BACKGROUND: Marijuana and alcohol are both substances that, when used Read more…
Related Articles A Cumulative Substance Use Score as a Novel Measure to Predict Risk of Criminal Recidivism in Forensic Juvenile Male Outpatients. Child Psychiatry Hum Dev. 2020 Apr 03;: Authors: Aebi M, Bessler C, Steinhausen HC Abstract This longitudinal study aimed to evaluate a newly developed cumulative measure for substance Read more…
Related Articles Drug Use Among Adolescents and Young Adults with Unsuppressed HIV Who Use Alcohol: Identifying Patterns of Comorbid Drug Use and Associations with Mental Health. AIDS Behav. 2020 Apr 04;: Authors: Starks TJ, MacDonell KK, Pennar AL, Dinaj-Koci V, Millar BM, Naar S Abstract Youth living with HIV (YLWH; Read more…
Related Articles Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967. Int J Mol Sci. 2020 Apr 01;21(7): Authors: Mason ER, Cummins TR Abstract Many epilepsy patients are refractory to conventional antiepileptic drugs. Resurgent and persistent currents can be enhanced by epilepsy mutations in the Read more…
Related Articles CBD Reverts the Mesenchymal Invasive Phenotype of Breast Cancer Cells Induced by the Inflammatory Cytokine IL-1β. Int J Mol Sci. 2020 Mar 31;21(7): Authors: García-Morales L, Castillo AM, Tapia Ramírez J, Zamudio-Meza H, Domínguez-Robles MDC, Meza I Abstract Cannabidiol (CBD) has been used to treat a variety of Read more…
Psychiatric comorbidity in compulsive sexual behavior disorder (CSBD). Addict Behav. 2020 Mar 07;107:106384 Authors: Ballester-Arnal R, Castro-Calvo J, Giménez-García C, Gil-Juliá B, Gil-Llario MD Abstract Compulsive Sexual Behavior Disorder (CSBD) is characterized by a persistent failure to control intense and recurrent sexual impulses, urges, and/or thoughts, resulting in repetitive sexual Read more…
MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages. J Neuroimmunol. 2020 Mar 20;343:577217 Authors: Fitzpatrick JM, Minogue E, Curham L, Tyrrell H, Gavigan P, Hind W, Downer EJ Abstract Toll-like receptors (TLRs) are sensors of pathogen-associated molecules that trigger inflammatory Read more…
Prolonged oral transmucosal delivery of highly lipophilic drug cannabidiol. Int J Pharm. 2020 Mar 31;:119276 Authors: Itin C, Barasch D, Domb AJ, Hoffman A Abstract Delivery of drugs through oral mucosa enables bypass of the gastrointestinal tract and « first pass » metabolism in the liver and the gut. Thus, a higher Read more…
Related Articles Risk Factor Reversal in Studies of Infectious Disease: Making Counterintuitive Results Intuitive Again. Sex Transm Dis. 2019 01;46(1):e5-e7 Authors: Kaufman JS, Banack HR, Adams JW, Marshall BDL, Stovitz SD Abstract A previously published study reported the seemingly paradoxical finding that men who have sex with men status was Read more…