Cannabidiol (CBD) reduces anxiety-related behavior in mice via an FMRP1-independent mechanism.

Utas.edu.au.3Zynerba Pharmaceuticals inc., Devon 19333, USA.4Department de la psychiatrie et des Sciences du comportement, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA.5Neuroscience Research Australia (NeuRA), NSW 2031, L’Australie ; École de médecine, Université de Western Sydney, NSW 2560, Australia.Abstract Syndrome de le X fragile est un trouble Read more…

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Selective activation of cannabinoid receptor-2 reduces neuroinflammation after traumatic brain injury via alternative macrophage polarization.

augusta.edu.Abstract Inflammation is an important mediator of secondary neurological injury after traumatic brain injury (TBI). Endocannabinoids, endogenously produced arachidonate based lipids, have recently emerged as powerful anti-inflammatory compounds, yet the molecular and cellular mechanisms underlying these effects are poorly defined. Endocannabinoids are physiological ligands for two known cannabinoid receptors, CB1R Read more…

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