Cannabinoid CB1 and CB2 receptor mechanisms underlie cannabis reward and aversion in rats.Spiller KJ1, Bi GH2, He Y2, Galaj E2, Gardner EL2, Xi ZX2.Author information1Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA, 19104, USA.2Molecular Targets and Medications Discovery Branch, Intramural Read more…
boystown.org.Abstract Alcohol and cannabis are two of the most commonly used substances by adolescents and are associated with adverse medical and psychiatric outcomes. These adverse psychiatric outcomes may reflect the negative impact of alcohol and/or cannabis abuse on neural systems mediating reward and/or error detection. However, work indicative of this Read more…
gmx.de.Abstract Public perception of cannabis as relatively harmless, alongside claimed medical benefits, have led to moves towards its legalization. Yet, long-term consequences of cannabis dependence, and whether they differ qualitatively from other drugs, are still poorly understood. A key feature of addictive drugs is that chronic use leads to adaptations Read more…
Zimmermann K1, Kendrick KM2, Scheele D1, Dau W3, Banger M3, Maier W4, Weber B5, Ma Y6, Hurlemann R1, Becker B7.Author information1Department of Psychiatry and Division of Medical Psychology, University of Bonn, 53105 Bonn, Germany.2MOE Key Laboratory for Neuroinformation, Center for Information in Medicine, Clinical Hospital of the Chengdu Brain Science Read more…