Cannabis Cannabinoid Res. 2021 Feb 12;6(1):1-4. doi: 10.1089/can.2020.0027. eCollection 2021.
Mankind has long utilized Cannabis for diverse purposes. However, it has only been since the late 19th century that its individual cannabinoids began to be isolated, analyzed, and synthesized. By the mid-20th century it was discovered that many cannabinoids were asymmetric, with chirality often controlling their pharmacology. Increasingly accurate measurement and understanding of cannabinoid chirality will facilitate their synthesis and accelerate their medicinal applications.
Source: ncbi 2