A Digital Health Tool to Understand and Prevent Cannabis-Impaired Driving Among Youth: A Cross-sectional Study of Responses to a Brief Intervention for Cannabis Use

JMIR Form Res. 2021 Mar 2;5(3):e25583. doi: 10.2196/25583. ABSTRACT BACKGROUND: Cannabis legalization has raised concern about an increased risk of cannabis-impaired driving, particularly among youth. Youth advocates and policy makers require cost-effective tools to target educational resources to promote responsible cannabis use. OBJECTIVE: The objective of this paper is threefold. Read more…

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The Impact of Depressed Mood and Coping Motives on Cannabis Use Quantity across the Menstrual Cycle in those with and without Pre-Menstrual Dysphoric Disorder

Addiction. 2021 Mar 2. doi: 10.1111/add.15465. Online ahead of print. ABSTRACT BACKGROUND AND AIMS: Reported rates of cannabis use among Canadian females are increasing. Female cannabis users progress to cannabis use disorder more rapidly than males (telescoping) and have higher rates of emotional disorder comorbidity. Addictive behaviors may change, along Read more…

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Self-blinding citizen science to explore psychedelic microdosing

Elife. 2021 Mar 2;10:e62878. doi: 10.7554/eLife.62878. ABSTRACT Microdosing is the practice of regularly using low doses of psychedelic drugs. Anecdotal reports suggest that microdosing enhances well-being and cognition; however, such accounts are potentially biased by the placebo effect. This study used a ‘self-blinding’ citizen science initiative, where participants were given Read more…

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Cannabis use and posttraumatic stress disorder comorbidity: Epidemiology, biology and the potential for novel treatment approaches

Int Rev Neurobiol. 2021;157:143-193. doi: 10.1016/bs.irn.2020.09.007. Epub 2021 Jan 19. ABSTRACT Cannabis use is increasing among some demographics in the United States and is tightly linked to anxiety, trauma, and stress reactivity at the epidemiological and biological level. Stress-coping motives are highly cited reasons for cannabis use. However, with increased Read more…

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Cannabinoids for major neurocognitive disorder: case report and literature review

Rev Colomb Psiquiatr. 2021 Jan-Mar;50(1):47-51. doi: 10.1016/j.rcp.2019.07.002. Epub 2020 Feb 3. ABSTRACT INTRODUCTION: Major neurocognitive disorder (MNCD) affects millions of people worldwide. However, the pharmacological options for its management are limited, ineffective and frequently associated with severe adverse reactions. CASE REPORT: An 85-year-old man with history of multiple chronic brain Read more…

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Modulation of the hypothalamic-pituitary-adrenal (HPA) axis by plants and phytonutrients: a systematic review of human trials

Nutr Neurosci. 2021 Mar 2:1-27. doi: 10.1080/1028415X.2021.1892253. Online ahead of print. ABSTRACT INTRODUCTION: The hypothalamic-pituitary-adrenal (HPA) axis plays a central role in the stress response. Plants, herbs, spices, and plant-based nutrients may influence HPA-axis activity. OBJECTIVE: To evaluate randomised controlled, human trials assessing the effects of single plants or phytonutrients Read more…

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Morbidity and mortality in schizophrenia with comorbid substance use disorders

Acta Psychiatr Scand. 2021 Mar 1. doi: 10.1111/acps.13291. Online ahead of print. ABSTRACT OBJECTIVE: Schizophrenia is highly comorbid with substance use disorders (SUD) but large epidemiological cohorts exploring the prevalence and prognostic significance of SUD are lacking. Here, we investigated the prevalence of SUD in patients with schizophrenia in Finland Read more…

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