Id1 and Sonic Hedgehog Mediate Cell Cycle Reentry and Apoptosis Induced by Amyloid Beta-Peptide in Post-mitotic Cortical Neurons.

ym.edu.tw.Abstract Amyloid beta-peptide (Aβ), the neurotoxic component of senile plaques in Alzheimer’s disease (AD) brains, is known to trigger cell cycle reentry in post-mitotic neurons followed by apoptosis. However, the underlying mechanisms remain unclear. Recently, we have reported that Aβs stimulate the expression of inhibitor of differentiation-1 (Id1) to induce Read more…

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Novel protective effect of O-1602 and abnormal cannabidiol, GPR55 agonists, on ER stress-induced apoptosis in pancreatic β-cells.

umac.mo.Abstract Insulin resistance and β-cell dysfunction are the main defects in Type 2 Diabetes Mellitus (T2DM), and β-cell dysfunction and apoptosis is the critical determinant in the progression of T2DM. G-protein coupled receptor 55 (GPR55) is an orphan G-protein coupled receptor, which is activated by endocannabinoids and lipid transmitters. Recently, Read more…

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Role of miRNA in the regulation of cannabidiol-mediated apoptosis in neuroblastoma cells.

Répertoire NCBI simple obtenir commencé NCBI formation NCBI aide NCBI manuel manuel & tutoriels soumettre des ressources de données chimiques & BioassaysData & SoftwareDNA & RNADomains & StructuresGenes & ExpressionGenetics & MedicineGenomes & MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyVariation populaire PubMed Bookshelf PubMed Central BLAST nucléotide génome SNP gène protéine PubChem vedette génétiques test Read more…

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Cannabidiol-induced apoptosis is mediated by activation of Noxa in human colorectal cancer cells.

korea.ac.kr.6Division of Oncology/Hematology, Department of Internal Medicine, College of Medicine, Korea University Medical Center, Korea University, Seoul, 08308, Republic of Korea; Graduate School of Medicine, College of Medicine, Korea University, Seoul, 08308, Republic of Korea. Electronic address: neogene View the Original article Partage le savoir

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