Riluzole blocks HU210-facilitated ventral tegmental long-term depression by enhancing glutamate uptake in astrocytes.

hust.edu.cn.Abstract The lifetime prevalence of addiction to cannabis (marijuana or cannabinoids) is among the highest of that of all illicit drugs in developed countries, and no effective treatment for cannabis addiction is currently available. Previous studies in our research group suggested that astrocyte-mediated long-term depression (LTD) in ventral tegmental area Read more…

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Substance type moderates the longitudinal association between depression and substance use from pre-treatment through a 1-year follow-up.

unc.edu.AbstractBACKGROUND: Research examining directionality of the relationship between depressive symptoms and substance use following treatment entry is limited. Furthermore, substances differ in their neurobiological effects on mood. The relationship between depression and substance use following treatment entry may be moderated by dependence on specific substances. The study tested (a) lagged Read more…

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Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis.

 61.3%). Conclusions and Relevance: Although individual-level risk remains moderate to low and results from this study should be confirmed in future adequately powered prospective studies, the high prevalence of adolescents consuming cannabis generates a large number of young people who could develop depression and suicidality attributable to cannabis. This is Read more…

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[Prevalence of major depression in France in the general population and in specific populations from 2000 to 2018: A systematic review of the literature].

ap-hm.fr.2Aix-Marseille université, faculté de médecine-Secteur Timone, EA 3279 : CEReSS-Centre d’étude et de recherche sur les services de santé et la qualité de vie, 27, boulevard Jean-Moulin, 13005 Marseille, France; Fondation FondaMental, 94000 Créteil, France.AbstractOBJECTIVE: To synthetize the data on the prevalence of major depressive disorders (MDD) in France in general Read more…

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Comorbid tobacco and other substance use and symptoms of anxiety and depression among hospitalised orthopaedic trauma patients.

McCrabb S1, Baker AL2, Attia J2,3,4, Balogh ZJ2,5, Lott N5, Palazzi K3, Naylor J6,7, Harris IA6,7, Doran CM8, George J9, Wolfenden L2,10, Skelton E2, Bonevski B2.Author information1School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, 1 University Drive, Callaghan, NSW, 2308, Australia. Sam.McCrabb View the Read more…

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