Memory deficits induced by chronic cannabinoid exposure are prevented by adenosine A2AR receptor antagonism.

Memory deficits induced by chronic cannabinoid exposure are prevented by adenosine A2AR receptor antagonism.Mouro FM1, Köfalvi A2, André LA1, Baqi Y3, Müller CE4, Ribeiro JA1, Sebastião AM5.Author information1Instituto de Farmacologia e Neurociências, Faculdade de Medicina, Universidade de Lisboa, Portugal; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Portugal.2CNC, Read more…

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Cannabidiol attenuates aggressive behavior induced by social isolation in mice: Involvement of 5-HT1A and CB1 receptors.

usp.br.3Department of Pharmacology, Medical School of Ribeirão Preto – University of São Paulo (FMRP-USP), 14049-900 Ribeirão Preto, São Paulo, Brazil.Abstract Long-term single housing increases aggressive behavior in mice, a condition named isolation-induced aggression or territorial aggression, which can be attenuated by anxiolytic, antidepressant, and antipsychotic drugs. Preclinical and clinical findings Read more…

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Cannabidiol attenuates aggressive behavior induced by social isolation in mice: Involvement of 5-HT1A and CB1 receptors.

USP.br.3Department de la pharmacologie, l’école médicale de Ribeirão Preto – Université de São Paulo (USP-FMRP) 14049-900 Ribeirão Preto, São Paulo, Brazil.Abstract Logement unique à long terme augmente le comportement agressif chez les souris, une condition nommée agression induite par l’isolement ou l’agression territoriale, qui peut être atténuée par des anxiolytiques, Read more…

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Id1 and Sonic Hedgehog Mediate Cell Cycle Reentry and Apoptosis Induced by Amyloid Beta-Peptide in Post-mitotic Cortical Neurons.

ym.edu.tw.Abstract Amyloid beta-peptide (Aβ), the neurotoxic component of senile plaques in Alzheimer’s disease (AD) brains, is known to trigger cell cycle reentry in post-mitotic neurons followed by apoptosis. However, the underlying mechanisms remain unclear. Recently, we have reported that Aβs stimulate the expression of inhibitor of differentiation-1 (Id1) to induce Read more…

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