Weighing the benefits and harms of psychotropic and analgesic substances – A perspective of German addiction medicine experts

Fortschr Neurol Psychiatr. 2021 Feb 25. doi: 10.1055/a-1363-0223. Online ahead of print. ABSTRACT BACKGROUND: In Europe, there have been several addiction-expert rankings of harms related to the use of psychotropic substances in the last 15 years. Among them, only one expert ranking took into account the potential benefits of these Read more…

Partage le savoir

A geospatiotemporal and causal inference epidemiological exploration of substance and cannabinoid exposure as drivers of rising US pediatric cancer rates

BMC Cancer. 2021 Feb 25;21(1):197. doi: 10.1186/s12885-021-07924-3. ABSTRACT BACKGROUND: Age-adjusted US total pediatric cancer incidence rates (TPCIR) rose 49% 1975-2015 for unknown reasons. Prenatal cannabis exposure has been linked with several pediatric cancers which together comprise the majority of pediatric cancer types. We investigated whether cannabis use was related spatiotemporally Read more…

Partage le savoir

Sleep-wake cycle disturbances and NeuN-altered expression in adult rats after cannabidiol treatments during adolescence

Psychopharmacology (Berl). 2021 Feb 26. doi: 10.1007/s00213-021-05769-z. Online ahead of print. ABSTRACT RATIONALE: The medical uses of cannabidiol (CBD), a constituent of the Cannabis sativa, have accelerated the legal and social acceptance for CBD-based medications but has also given the momentum for questioning whether the long-term use of CBD during Read more…

Partage le savoir

Methylomic Investigation of Problematic Adolescent Cannabis Use and Its Negative Mental Health Consequences

J Am Acad Child Adolesc Psychiatry. 2021 Feb 18:S0890-8567(21)00084-8. doi: 10.1016/j.jaac.2021.02.008. Online ahead of print. ABSTRACT OBJECTIVE: The impact of adolescent cannabis use is a pressing public health question due to the high rates of use and links to negative outcomes. Here we consider the association between problematic adolescent cannabis Read more…

Partage le savoir

Piloting a brief intervention plus mobile boosters for drug use among emerging adults receiving emergency department care

Drug Alcohol Depend. 2021 Feb 16;221:108625. doi: 10.1016/j.drugalcdep.2021.108625. Online ahead of print. ABSTRACT PURPOSE: There are few efficacious prevention interventions for emerging adults (ages 18-25) drug use and concomitant risks (e.g., sexual risk behaviors). We developed and evaluated the feasibility and acceptability of an Emergency Department (ED)-initiated brief intervention (BI) Read more…

Partage le savoir

The Effect of Cannabis on the Clinical and Cytokine Profiles in Patients with Multiple Sclerosis

Mult Scler Int. 2021 Feb 5;2021:6611897. doi: 10.1155/2021/6611897. eCollection 2021. ABSTRACT BACKGROUND: Multiple studies have reported that cannabis administration in multiple sclerosis patients is associated with decreased symptom severity. This study was conducted to evaluate the prevalence of cannabis abuse in multiple sclerosis cases and to evaluate the effect of Read more…

Partage le savoir

Cannabinoid Hyperemesis Syndrome: A Case Study in a Tunisian Young Man

Case Rep Med. 2021 Feb 6;2021:6617148. doi: 10.1155/2021/6617148. eCollection 2021. ABSTRACT The increasing prevalence of cannabis use in the world requires awareness of cannabis-related disorders such as cannabinoid hyperemesis syndrome. This syndrome includes cyclic episodes of nausea, vomiting, and the learned behavior of hot bathing in individuals with chronic cannabis Read more…

Partage le savoir
error: Content is protected !!