Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy.

Bar-Lev Schleider L1,2, Mechoulam R3, Saban N2, Meiri G4,5, Novack V6.Author information1Clinical Cannabis Research Institute, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Be’er-Sheva, Israel.2Research Department, Tikun Olam LTD, Tel Aviv-Yafo, Israel.3Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, Read more…

Partage le savoir

Preclinical safety and efficacy of cannabidivarin for early life seizures.

georgetown.edu.Abstract A significant proportion of neonatal and childhood seizures are poorly controlled by existing anti-seizure drugs (ASDs), likely due to prominent differences in ionic homeostasis and network connectivity between the immature and mature brain. In addition to the poor efficacy of current ASDs, many induce apoptosis, impair synaptic development, and Read more…

Partage le savoir

Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and Meta-Analysis.

 50% reduction in monthly seizure frequency during the treatment period and the incidence of treatment withdrawal and adverse events (AEs). RESULTS: Four trials involving 550 patients with Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS) were included. The pooled average difference in change in seizure frequency during the treatment period resulted Read more…

Partage le savoir

Efficacy and Safety of Adjunctive Cannabidiol in Patients with Lennox-Gastaut Syndrome: A Systematic Review and Meta-Analysis.

 50% reduction in baseline drop and non-drop seizure frequency, and the incidence of treatment withdrawal and adverse events (AEs). Risk ratios (RRs) with 95% confidence intervals (CIs) were estimated through the inverse variance method. RESULTS: Two trials were included involving 396 participants. Patients presenting  View the Original article Partage le Read more…

Partage le savoir
error: Content is protected !!