Gene-environment interaction between an endocannabinoid system genetic polymorphism and cannabis use in first episode of psychosis.

clinic.cat.2Department of Pathological Anatomy, Pharmacology and Microbiology, University of Barcelona, Institutd’InvestigacionsBiomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. CIBERSAM; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Spain.3Department of Clinical and Experimental Medicine, Psychiatry Unit, University of Catania, Catania, Italy.4Barcelona Clínic Schizophrenia Unit, Hospital Clínic de Barcelona, Barcelona, Read more…

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Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors.

ufpr.br.Abstract Most diabetic patients describe moderate to severe pain symptoms whose pharmacological treatment is palliative and poorly effective. Cannabidiol (CBD) has shown promising results in painful conditions. Then, we aimed to investigate the potential antinociceptive effect of CBD over the mechanical allodynia in streptozotocin-induced diabetic (DBT) rats, as well as Read more…

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Effects of nicotine and THC vapor inhalation administered by an electronic nicotine delivery system (ENDS) in male rats.

scripps.edu.AbstractBACKGROUND: Electronic nicotine delivery systems (ENDS, e-cigarettes) are increasingly used for the self-administration of nicotine by various human populations, including previously nonsmoking adolescents. Studies in preclinical models are necessary to evaluate health impacts of ENDS including the development of nicotine addiction, effects of ENDS vehicles, flavorants and co-administered psychoactive substances Read more…

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The Endocannabinoid System and Cannabidiol’s Promise for the Treatment of Substance Use Disorder.

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Cannabis, cannabinoid receptors, and endocannabinoid system: yesterday, today, and tomorrow.

Simple NCBI Directory Getting Started NCBI Education NCBI Help Manual NCBI Handbook Training & Tutorials Submit Data Resources Chemicals & BioassaysData & SoftwareDNA & RNADomains & StructuresGenes & ExpressionGenetics & MedicineGenomes & MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyVariation Popular PubMed Bookshelf PubMed Central BLAST Nucleotide Genome SNP Gene Protein PubChem Featured Genetic Testing Registry Read more…

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Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System.

Simple NCBI Directory Getting Started NCBI Education NCBI Help Manual NCBI Handbook Training & Tutorials Submit Data Resources Chemicals & BioassaysData & SoftwareDNA & RNADomains & StructuresGenes & ExpressionGenetics & MedicineGenomes & MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyVariation Popular PubMed Bookshelf PubMed Central PubMed Health BLAST Nucleotide Genome SNP Gene Protein PubChem Featured Genetic Read more…

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